A study for patients with a cough or bowel symptoms such as loose stool
The majority of patients who come to their doctor with lung symptoms (for example cough) or bowel symptoms (for example loose stool) do not have anything seriously wrong. However, a very few people are at risk of cancer. We would like to help doctors diagnose cancer quickly so that potential high risk patients are detected sooner and unnecessary examinations are minimised for those patients that are low risk. This research is about finding what symptoms and examinations are best for predicting lung and bowel cancer.
The study is open to those who have visited their GP with symptoms that we are interested in, as listed above. This will help us develop a way for minimising unnecessary examinations for low risk people and develop a speedy diagnosis for high risk people. You will be one of 20,000 people with lung and bowel symptoms asked to take part in this research.
What do I have to do?
You will be asked to provide a blood/saliva sample as well as being asked to complete a questionnaire.
A study for patients with new joint symptoms or family members of patients with rheumatoid arthritis (RA).
Rheumatoid arthritis is associated with markers in the blood such as anti-CCP antibodies.
We would like to assess whether anti –CCP antibodies are present in samples other than the blood. These are samples which originate from different sites within the body e.g. stools which represents the gut, sputum which represents the lungs and fluid from near the gums which represents the mouth. These sites are called mucosal sites. All of these mucosal sites have been associated with possibly triggering autoimmune disease like rheumatoid arthritis. By taking samples from these sites we can determine whether they could be involved in causing or triggering rheumatoid arthritis in the future.
What do I have to do?
You will be asked to provide a stool and sputum sample, and undergo a dental assessment.
If you are interested or think you could participate in any of the trials, please speak to one of our patient advisors who will be able to help you.